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1

Lung Cancer

Herbst, Roy S., Heymach, John V., Lippman, Scott M.

Journal:

Boston Medical and Surgical Journal

Year:

2008

Language:

english

File:

PDF, 728 KB

english, 2008

2

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

Rudin, Charles M., Poirier, John T., Byers, Lauren Averett, Dive, Caroline, Dowlati, Afshin, George, Julie, Heymach, John V., Johnson, Jane E., Lehman, Jonathan M., MacPherson, David, Massion, Pierre

Journal:

Nature Reviews Cancer

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

3

Prognostic Impact of Radiation Therapy to the Primary Tumor in Patients With Non-small Cell Lung Cancer and Oligometastasis at Diagnosis

Jose Luis Lopez Guerra, Daniel Gomez, Yan Zhuang, David S. Hong, John V. Heymach, Stephen G. Swisher, Steven H. Lin, Ritsuko Komaki, James D. Cox, Zhongxing Liao

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 501 KB

english, 2012

4

Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches

Parra, Edwin R., Villalobos, Pamela, Behrens, Carmen, Jiang, Mei, Pataer, Apar, Swisher, Stephen G., William, William N., Zhang, Jiexin, Lee, Jack, Cascone, Tina, Heymach, John V., Forget, Marie-André

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

5

Subcellular localization of epitope-tagged neurotrophins in neuroendocrine cells

J. Carsten Möller, Alex Krüttgen, John V. Heymach Jr., Nafisa Ghori, Eric M. Shooter

Journal:

Journal of Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 405 KB

english, 1998

6

Circulating biomarkers for vascular endothelial growth factor inhibitors in renal cell carcinoma

Amado J. Zurita, Eric Jonasch, Hua-Kang Wu, Hai T. Tran, John V. Heymach

Journal:

Year:

2009

Language:

english

File:

PDF, 201 KB

english, 2009

7

A phase 2 pilot trial of low-dose, continuous infusion, or “metronomic” paclitaxel and oral celecoxib in patients with metastatic melanoma

Rupal S. Bhatt, Jaime Merchan, Robert Parker, Hua-Kang Wu, Liang Zhang, Virginia Seery, John V. Heymach, Michael B. Atkins, David McDermott, Vikas P. Sukhatme

Journal:

Year:

2010

Language:

english

File:

PDF, 139 KB

english, 2010

8

A novel therapeutic combination for neuroblastoma : The vascular endothelial growth factor receptor/epidermal growth factor receptor/rearranged during transfection inhibitor vandetanib with 13-cis-retinoic acid

Peter E. Zage, Lizhi Zeng, Shana Palla, Wendy Fang, Monique B. Nilsson, John V. Heymach, Patrick A. Zweidler-McKay

Journal:

Year:

2010

Language:

english

File:

PDF, 629 KB

english, 2010

9

Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells

Tina Cascone, Maria Pia Morelli, Floriana Morgillo, Woo-Young Kim, Gabriella Rodolico, Stefano Pepe, Liberato Berrino, Ho-Young Lee, John V. Heymach, Fortunato Ciardiello

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 356 KB

english, 2008

10

Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells

Tina Cascone, Maria Pia Morelli, Floriana Morgillo, Woo-Young Kim, Gabriella Rodolico, Stefano Pepe, Giampaolo Tortora, Liberato Berrino, Ho-Young Lee, John V. Heymach, Fortunato Ciardiello

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

11

Dr. Folkman's legacy—a life of angiogenesis research : Editorial

GEORGE N. NAUMOV, JOHN HEYMACH, LARS A. AKSLEN

Journal:

Year:

2008

Language:

english

File:

PDF, 113 KB

english, 2008

12

Neuronal self-reliance

Heymach, John V., Barres, Barbara A.

Journal:

Year:

1995

File:

PDF, 264 KB

1995

13

10.1038/39743

Heymach, John V., Barres, Barbara A.

Journal:

Year:

1997

Language:

english

File:

PDF, 118 KB

english, 1997

14

Angiogenesis inhibitors and hypoxia

Kieran, Mark W., Folkman, Judah, Heymach, John

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 73 KB

english, 2003

15

Molecular targets for cancer chemoprevention

William, William N., Heymach, John V., Kim, Edward S., Lippman, Scott M.

Journal:

Nature Reviews Drug Discovery

Year:

2009

Language:

english

File:

PDF, 485 KB

english, 2009

16

Circulating Biomarkers in Advanced Renal Cell Carcinoma: Clinical Applications

Maria Hernandez-Yanez, John V. Heymach, Amado J. Zurita

Journal:

Current Oncology Reports

Year:

2012

Language:

english

File:

PDF, 210 KB

english, 2012

17

Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells

Xiaoying Liu, Wei Guo, Shuhong Wu, Li Wang, Ji Wang, Bingbing Dai, Edward S. Kim, John V. Heymach, Michael Wang, Luc Girard, John Minna, Jack A. Roth, Stephen G. Swisher, Bingliang Fang

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

18

The Clinical Development of Vandetanib: Updates on Ongoing Phase III Clinical Trials in Advanced Non—Small-Cell Lung Cancer

Journal:

Clinical Lung Cancer

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

19

Emerging Antiangiogenic Agents in Lung Cancer

David Lee, John V. Heymach

Journal:

Clinical Lung Cancer

Year:

2006

Language:

english

File:

PDF, 875 KB

english, 2006

20

Endothelial progenitor cells contribute to accelerated liver regeneration

Paul Beaudry, Yasuhiro Hida, Taturo Udagawa, Ian P. Alwayn, Arin K. Greene, Danielle Arsenault, Judah Folkman, John V. Heymach, Sandra Ryeom, Mark Puder

Journal:

Journal of Pediatric Surgery

Year:

2007

Language:

english

File:

PDF, 830 KB

english, 2007

21

Inhibition of Intra-Abdominal Adhesion Formation With the Angiogenesis Inhibitor Sunitinib

Sendia Kim, Sang Lee, Arin K. Greene, Danielle A. Arsenault, Hau Le, Jonathan Meisel, Katherine Novak, Evelyn Flynn, John V. Heymach, Mark Puder

Journal:

Journal of Surgical Research

Year:

2008

Language:

english

File:

PDF, 208 KB

english, 2008

22

Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells

Dhara N. Amin, Diane R. Bielenberg, Eugene Lifshits, John V. Heymach, Michael Klagsbrun

Journal:

Microvascular Research

Year:

2008

Language:

english

File:

PDF, 490 KB

english, 2008

23

Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial

Roy S Herbst, Yan Sun, Wilfried EE Eberhardt, Paul Germonpré, Nagahiro Saijo, Caicun Zhou, Jie Wang, Longyun Li, Fairooz Kabbinavar, Yukito Ichinose, Shukui Qin, Li Zhang, Bonne Biesma, John V Heymach

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 327 KB

english, 2010

24

Phase 1–2 study of docetaxel plus aflibercept in patients with recurrent ovarian, primary peritoneal, or fallopian tube cancer

Robert L Coleman, Linda R Duska, Pedro T Ramirez, John V Heymach, Aparna A Kamat, Susan C Modesitt, Kathleen M Schmeler, Revathy B Iyer, Michael E Garcia, Debbie L Miller, Edward F Jackson, Chaan S Ng

Journal:

The Lancet Oncology

Year:

2011

Language:

english

File:

PDF, 208 KB

english, 2011

25

Positron Emission Tomography/Computed Tomography-Guided Intensity-Modulated Radiotherapy for Limited-Stage Small-Cell Lung Cancer

Shervin M. Shirvani, Ritsuko Komaki, John V. Heymach, Frank V. Fossella, Joe Y. Chang

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2012

Language:

english

File:

PDF, 433 KB

english, 2012

26

Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials

Hai T Tran, Yuan Liu, Amado J Zurita, Ying Lin, Katherine L Baker-Neblett, Anne-Marie Martin, Robert A Figlin, Thomas E Hutson, Cora N Sternberg, Rafael G Amado, Lini N Pandite, John V Heymach

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 623 KB

english, 2012

27

Dual Targeting of the Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptor Pathways: Rationale and Clinical Applications for Non-Small-Cell Lung Cancer

Lauren A. Byers, John V. Heymach

Journal:

Clinical Lung Cancer

Year:

2007

Language:

english

File:

PDF, 164 KB

english, 2007

28

Circulating Biomarkers of Response to Sunitinib in Gastroenteropancreatic Neuroendocrine Tumors

Mateo, Joaquin, Heymach, John V., Zurita, Amado J.

Journal:

Molecular Diagnosis & Therapy

Year:

2012

Language:

english

File:

PDF, 170 KB

english, 2012

29

Modulation of c-Met signaling and cellular sensitivity to radiation

Bhardwaj, Vikas, Cascone, Tina, Cortez, Maria Angelica, Amini, Arya, Evans, Jaden, Komaki, Ritsuko U., Heymach, John V., Welsh, James W.

Journal:

Year:

2013

Language:

english

File:

PDF, 180 KB

english, 2013

30

Neurotrophins Induce Release of Neurotrophins by the Regulated Secretory Pathway

Alex Kruttgen, J. Carsten Moller, John V. Heymach and Eric M. Shooter

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.80 MB

english, 1998

31

Phase I Trial of Cisplatin, Pemetrexed, and Imatinib Mesylate in Chemonaive Patients With Unresectable Malignant Pleural Mesothelioma

Tsao, Anne S., Harun, Nusrat, Lee, J. Jack, Heymach, John, Pisters, Katherine, Hong, Waun Ki, Fujimoto, Junya, Wistuba, Ignacio

Journal:

Clinical Lung Cancer

Year:

2014

Language:

english

File:

PDF, 192 KB

english, 2014

32

Propensity Score–Matched Analysis of Comprehensive Local Therapy for Oligometastatic Non-Small Cell Lung Cancer That Did Not Progress After Front-Line Chemotherapy

Sheu, Tommy, Heymach, John V., Swisher, Stephen G., Rao, Ganesh, Weinberg, Jeffrey S., Mehran, Reza, McAleer, Mary Frances, Liao, Zhongxing, Aloia, Thomas A., Gomez, Daniel R.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2014

Language:

english

File:

PDF, 322 KB

english, 2014

33

Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis

Herbst, Roy S, Heymach, John V, O’Reilly, Michael S, Onn, Amir, Ryan, Anderson J

Journal:

Expert Opinion on Investigational Drugs

Year:

2007

Language:

english

File:

PDF, 314 KB

english, 2007

34

[IEEE 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - Washington, DC, USA (2012.12.2-2012.12.4)] Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) - Latent feature decompositions for integrative analysis of diverse high-throughput genomic data

Gregory, Karl B., Coombes, Kevin R., Momin, Amin, Girard, Luc, Byers, Lauren A., Lin, Steven, Peyton, Michael, Heymach, John V., Minna, John D., Baladandayuthapani, Veerabhadran

Year:

2012

Language:

english

File:

PDF, 201 KB

english, 2012

35

Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

Hao, Chuncheng, Wang, Li, Peng, Shaohua, Cao, Mengru, Li, Hongyu, Hu, Jing, Huang, Xiao, Liu, Wei, Zhang, Hui, Wu, Shuhong, Pataer, Apar, Heymach, John V., Eterovic, Agda Karina, Zhang, Qingxiu, Shaw,

Journal:

Year:

2015

Language:

english

File:

PDF, 766 KB

english, 2015

36

A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non–Small-Cell Lung Cancer

Lin, Steven H., Zhang, Jing, Giri, Uma, Stephan, Clifford, Sobieski, Mary, Zhong, Ling, Mason, Kathy A., Molkentine, Jessica, Thames, Howard D., Yoo, Stephen S., Heymach, John V.

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 2.94 MB

english, 2014

37

Targeted Therapies for Lung Cancer

Larsen, Jill E., Cascone, Tina, Gerber, David E., Heymach, John V., Minna, John D.

Journal:

The Cancer Journal

Year:

2011

Language:

english

File:

PDF, 306 KB

english, 2011

38

Membrane Carbonic Anhydrase IX Expression and Relapse Risk in Resected Stage I–II Non–Small-Cell Lung Cancer

Stewart, David J., Nunez, Maria I., Behrens, Carmen, Liu, Diane, Lin, Yan Heather, Lee, J. Jack, Roth, Jack, Heymach, John, Swisher, Stephen G., Hong, Waun Ki, Wistuba, Ignacio Ivan

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 703 KB

english, 2014

39

Systemic and CNS activity of the RET inhibitor vandetanib combined with the mTOR inhibitor everolimus in KIF5B-RET re-arranged non-small cell lung cancer with brain metastases

Subbiah, Vivek, Berry, Jenny, Roxas, Michael, Guha-Thakurta, Nandita, Subbiah, Ishwaria Mohan, Ali, Siraj M., McMahon, Caitlin, Miller, Vincent, Cascone, Tina, Pai, Shobha, Tang, Zhenya, Heymach, John

Journal:

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

40

Vandetanib, A Dual Inhibitor of VEGFR and EGFR Tyrosine Kinase Activity

Troiani, Teresa, Cascone, Tina, Heymach, John, Ciardiello, Fortunato

Journal:

Current Cancer Therapy Reviews

Year:

2007

Language:

english

File:

PDF, 145 KB

english, 2007

41

The mutually regulatory loop of epithelial–mesenchymal transition and immunosuppression in cancer progression

Chen, Limo, Heymach, John V, Qin, F Xiao-Feng, Gibbons, Don L

Journal:

Year:

2015

Language:

english

File:

PDF, 500 KB

english, 2015

42

Predictive biomarkers in precision medicine and drug development against lung cancer

Fang, Bingliang, Mehran, Reza J, Heymach, John V, Swisher, Stephen G

Journal:

Chinese Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 2.05 MB

english, 2015

43

In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation

Cortez, Maria Angelica, Valdecanas, David, Niknam, Sharareh, Peltier, Heidi J, Diao, Lixia, Giri, Uma, Komaki, Ritsuko, Calin, George A, Gomez, Daniel R, Chang, Joe Y, Heymach, John Victor, Bader, And

Journal:

Molecular Therapy — Nucleic Acids

Year:

2015

Language:

english

File:

PDF, 2.49 MB

english, 2015

44

Human Bronchoalveolar Fibronectin

Villiger, Beat, Heymach, George J., Broekelmann, Thomas J., Kelley, Diane G., Kuhn, Charles, McDonald, John A.

Journal:

Year:

1982

Language:

english

File:

PDF, 2.02 MB

english, 1982

45

Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2

Le, Xiao-Feng, Mao, Weiqun, Lu, Chunhua, Thornton, Angela, Heymach, John V., Sood, Anil K., Bast, Jr., Robert C.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.52 MB

english, 2008

46

Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients With Lung Adenocarcinoma

Lou, Yanyan, Pecot, Chad V., Tran, Hai T., DeVito, Vikki J., Tang, Xi Ming, Heymach, John V., Luthra, Raja, Wistuba, Ignacio I., Zuo, Zhuang, Tsao, Anne S.

Journal:

Clinical Lung Cancer

Year:

2016

Language:

english

File:

PDF, 1015 KB

english, 2016

47

Second-Line Treatment of Advanced Non-small Cell Lung Cancer

Gridelli, Cesare, Ardizzoni, Andrea, Ciardiello, Fortunato, Hanna, Nasser, Heymach, John V., Perrone, Francesco, Rosell, Rafael, Shepherd, Frances A., Thatcher, Nick, Vansteenkiste, Johan, De Petris,

Journal:

Journal of Thoracic Oncology

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

48

Axl Receptor Axis: A New Therapeutic Target in Lung Cancer

Levin, Pavel A., Brekken, Rolf A., Byers, Lauren Averett, Heymach, John V., Gerber, David E.

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 842 KB

english, 2016

49

SABR vs surgery for NSCLC in the media

Rice, David, Sepesi, Boris, Heymach, John, Swisher, Stephen, Vaporciyan, Ara

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

50

Angiogenesis Inhibitors for Lung Cancer: Clinical Developments and Future Directions

Blumenschein, George, Heymach, John V.

Journal:

Journal of Thoracic Oncology

Year:

2006

Language:

english

File:

PDF, 279 KB

english, 2006